We use 'differ' when two things are not the same. It shows difference between people, ideas, or things.
My idea differs from yours.
Their opinions differ a lot.
'Differ' can mean you don’t agree with someone’s opinion. It shows a difference in ideas or choices.
We differ on the best way to study.
She differs with him about the plan.
'Differ' is used to talk about things or people that have different features or qualities from others in the same group.
Species differ in color and size.
People differ in their skills.